zoom Excess shipyard capacity and a slowing but still considerable orderbook are the negative factors overhanging brighter prospects for shipping demand growth, according to Maritime Strategies International (MSI).MSI has forecast a structural change to future shipping cycles, “with shorter, sharper cycles with any bull run culled by the relative rapid delivery of legions of ships via the new dynamic shipyard capacity landscape,” Adam Kent, MSI consultant, said.Kent said that, looking at Compound Annual Growth Rates based on MSI’s assessment of demand in a number of major shipping sectors, crude tankers, containers, chemical tankers all have better prospects over the next five years.“Convert this into growth in shipping requirements by factoring in distances, speed, port times, waiting time and ballast ratios, the picture becomes even more positive for crude tankers and containers, chemical tankers and LNG carriers,” according to MSI.However, the supply side remains the source of most problems and despite some recent corrections, the orderbook still casts a long shadow over most sectors. Across all the main commodity sectors the orderbook significantly outstrips the ageing fleet with MPP, Ro-Ro and PCTC the only sectors where there is a better balance of replacement tonnage requirements.MSI said that shipyards will still be hungry for orders because, based on scheduled orderbooks and maximum historical output, the three main shipbuilding nations are only fully utilised for 2016. In 2017 utilisation drops to around 70% in Korea and Japan and is close to 50% in China.
TORONTO – Researchers say changes to Ontario’s cervical cancer screening guidelines have led to thousands of women not being tested and diagnosed for chlamydia.Chlamydia is the world’s most common sexually transmitted disease; left untreated, the bacterial infection can lead to pelvic inflammatory disease, ectopic pregnancy and infertility.Two years after Ontario’s cervical cancer screening guidelines changed in 2012, chlamydia testing dropped 26 per cent in females aged 15 to 19 and 18 per cent in those aged 20 to 24 — with more than 2,700 fewer cases being detected.The new guidelines recommend that women who have been sexually active receive a Pap test every three years starting at age 21, instead of having one annually starting three years after becoming sexually active.Doctors usually collect swabs to screen for sexually transmitted infections like chlamydia while doing a Pap test for cervical cancer.The researchers hope greater public awareness about the need for young women to be tested for chlamydia and the availability of a simple urine test will lead to more screening.“From a public health perspective, it is important to ensure that chlamydia cases are diagnosed in order to limit the spread of infection and the longer-term impacts of this infection if it isn’t caught and treated,” said co-author Dr. Jeff Kwong, a scientist at Public Health Ontario and the Institute for Clinical Evaluative Sciences.“This is particularly true for women younger than 21 years of age who are at risk for chlamydia if they are sexually active and who no longer warrant cervical cancer screening,” he said. “This research shows that women should be tested for chlamydia based on risk, regardless of the need for Pap tests.”The findings are published in the July 10 issue of the Annals of Family Medicine.
Canadian Prime Minister Justin Trudeau, Vancouver Film School founder James Griffin, Digital India’s Ashish Kulkarni, and Canadian Defence Minister Harjit Sajjan attended a meeting in India. VFS founder and president James Griffin attended a meeting in Mumbai with Trudeau, Canadian Defence Minister Harjit Sajjan, and Digital India’s Ashish Kulkarni, who is the Federation of Indian Chambers of Commerce and Industry’s chairman for animation, visual effects, gaming, and comics. Advertisement Advertisement Facebook Advertisement LEAVE A REPLY Cancel replyLog in to leave a comment Login/Register With: As Mumbai, India, is the nexus of the world’s most prolific film production centres, the Hindi film industry otherwise known as Bollywood, a local film school is planning to expand there.On February 20, the Vancouver Film School announced that it will be opening a new campus in Mumbai in July, located at the Mackichan Complex of Wilson College.The partnership was one of 66 commercial contracts by Canadian and Indian companies announced by Canadian Prime Minister Trudeau during his visit to India. Twitter
New Delhi: Manipal Hospitals has launched first of its kind ‘Suraksha Card’, a healthcare privilege membership programme aimed at providing best of hospital care to the patients at affordable costs.The benefits of Suraksha Card include unlimited OPD consultations for a year, 15 per cent discount on lab & radiology investigations, 10 per cent discount on pharmacy, one preventive health check package worth 499 free in a year, free ambulance pick up, free home sample collection and 10 per cent discount on IPD – room rent only. These benefits can be availed for a year with a one-time payment of Rs 2000 per person. In addition, the beneficiaries can also add their family members by availing the card for Rs 3,000 for 2-4 members and Rs 4,000 for 5-6 members.
Geneva – Morocco condemned, on Monday in Geneva, Algeria’s maneuvers before the UN Human Rights Council (UNHRC) to mislead the international community regarding the situation in the Kingdom’s southern provinces (the so-called Western Sahara).In a speech before the Council on behalf of a group of countries including Guinea, Senegal, Central Africa and the Comoro Islands, Morocco’s permanent representative to Geneva, Ambassador Mohamed Auajjar, recalled that since Spain’s departure in 1975, the Moroccan Sahara issue has become a regional political dispute on the agenda of the UN Security Council.“In keeping with its political commitment and in response to calls made by the UNSC since 2004, Morocco submitted to the UN in 2007 an initiative to negotiate a status of autonomy for the Sahara region which meets the right to self-determination of the populations concerned while respecting Morocco’s sovereignty and territorial integrity,” he said. The ambassador noted that, instead of engaging in good faith in the negotiation process triggered in 2007, the other parties chose to take an obstructionist position based on the instrumentalization of human rights in order to hamper UN efforts to find a negotiated political solution on the basis of the autonomy plan.While continuing its cooperation with the UN to revive the political talks process, Morocco has pursued pioneering democratic reforms in the region so as to foster the rule of law and broaden the scope of liberties in its national territory, he added.With MAP
TORONTO — The Toronto stock market was higher Tuesday on a day marked by volatility and a sell-off in commodities.The S&P/TSX composite index closed up 30.93 points at 14,624.50 after falling more than 200 points earlier in the session.Stocks in New York also rebounded after opening the day with significant losses.The Dow Jones industrial average closed up 93.33 points at 17,776.91 after being down more than 200 points, while the Nasdaq rose 5.52 points to 4,997.46 after earlier shedding more than 90 points. The S&P 500 finished 12.58 points higher at 2,081.34 after sliding nearly 25 points in early trading.Sunday’s “no” vote in the Greek debt referendum plunged the country’s future in the euro into uncertainty, yet investors are now adjusting their expectations on the fallout in world financial markets, according to Sadiq Adatia, chief investment officer for Sun Life Global Investments.“People realized around the same time that whatever happens with Greece, it’s still a really small economy,” he said. “You’ve still got to worry about the rest of the world and there could be opportunity there.” Commodities were hit hard, with oil, gold, and copper all losing value.The August contract for benchmark crude ended the day down 20 cents at US$52.33 a barrel.“People are starting to realize that supply hasn’t diminished, it’s actually gone up since we hit $44 oil in January,” Adatia said. “The next step is down rather than up for oil prices.”The August gold contract was down $20.60 at US$1,154.30 an ounce, while September copper fell 9.15 cents to US$2.45 a pound, reaching levels not seen since January.The loonie slid 0.37 of a US cent to end the day at 78.67 cents, its sixth consecutive day of losses against the greenback.In the face of the Greek crisis, Adatia said, investors have become risk averse and are flocking to the safety of the American currency, pushing up its value relative to the Canadian dollar.The loonie has also been under pressure from speculation that the Bank of Canada will cut its trend-setting interest rate next Wednesday.Much of that has come from economic reports indicating that Canada may be in a recession — defined as two consecutive quarters of negative growth.Statistics Canada added more fuel to the fire Tuesday when it reported that Canada’s merchandise trade deficit rose to $3.34 billion in May from $3.0 billion in April, a gap that was much higher than the consensus estimate of $2.5 billion.Trade figures showed that exports declined 0.6 per cent in May to $42 billion, while imports edged up 0.2 per cent to $45.3 billion.
Environment Canada has issued a special weather statement for the GTA with 5 to 10 centimetres of snow in the forecast. The area affected is the north shore of Lake Ontario from Burlington east to Belleville. Steady snowfall has created a tough drive for commuters. Highways and roadways are slick, and many areas are still backed up with traffic moving much slower than usual. It’s been a wintry week, weather-wise, but the season doesn’t officially begin until Saturday. However cold weather alerts issued for Hamilton and Toronto have been cancelled. Video: Sean Leathong tracks the winter weather cleanup while Matt Hayes talks about how long this is going to be with us.
After sitting out 3 games with an undisclosed suspension, sophomore forward Marc Loving is set to make his return against Michigan State on Feb. 13.Credit: Samantha Hollingshead / Lantern photographerThe Ohio State men’s basketball team has won five of its past six games, with the one setback coming in the first game of Marc Loving’s three-game suspension.Coach Thad Matta confirmed Friday the sophomore forward will make his return to the court against Michigan State on Saturday, with the Buckeyes looking to make it three wins in a row.Matta said Loving “definitely” makes OSU a better team, but added the Buckeyes have improved overall in the time he missed.“I like the strides that everybody on this team has made in his (Loving’s) absence,” Matta said.Loving’s suspension was announced just before the Buckeyes took on Purdue on Feb. 4 in West Lafayette, Ind. That game ended in a 60-58 OSU loss, then Loving missed out on the Buckeyes’ next road trip as well.But that time around OSU came out on top with a 19-point shellacking of Rutgers on the road Feb. 8 before trouncing Penn State, 75-55, at home on Feb. 11. Matta stressed the improvement over those three games, and said he’s not sure exactly how Loving will slot into the lineup against the Spartans.“Now where does he come back and fit in?” Matta said. “Hopefully like he did in the Maryland game.”The Buckeyes took on Maryland the game before Loving’s suspension, and the Toledo native made the most of 31 minutes off the bench, going 5-for-5 from 3-point land and tying his career high with 19 points.Against Purdue, the Buckeyes didn’t have Loving’s production as the player behind him — freshman forward Keita Bates-Diop — didn’t attempt a shot. But against Rutgers, Bates-Diop scored a career-high 14 points, and added seven more against the Nittany Lions.Bates-Diop said he took his chance with Loving out of the lineup, but added having him back in the lineup will give OSU a boost.“I saw it (Loving’s suspension) as an opportunity to step up and play well, and I did,” Bates-Diop said Friday. “Having Marc back, it just makes us a better team, it makes us a deeper team.”Senior center Amir Williams said Loving’s return will be “huge” for OSU because of his ability to bring multiple new dimensions to the offense.“(Loving’s) a guy that can stretch the floor,” Williams said Friday. “He can create his own shot by driving to the basket, he can also post up. He just provides different ways of scoring the basketball, so it’s definitely gonna be huge having him back this game.”With Loving’s added dimension out of the equation, the loss to Purdue marked the first time the Buckeyes were held to less than 60 points since a loss to Louisville back on Dec. 2.Matta said the Boilermakers’ defensive scheme is similar to what he expects from Michigan State, with the difference being that the Spartans will have to deal with Loving in addition to the scoring prowess of freshman guard D’Angelo Russell.“They (Michigan State) are a very active gap-oriented type team,” Matta said. “The principles that their defense is based on is very sound, just in terms of keeping guys in front of you, being physical on the cuts, stuff like that.”In addition to tough defense, Williams said the Buckeyes will be playing in one of the most hostile environments the Big Ten has to offer.“It ranks definitely in the top in the Big Ten, that student section can get pretty loud,” he said of Michigan State’s Breslin Student Events Center. “When they score the first basket the arena goes crazy, they start popping things and throwing things in the air.“It’s gonna be tough, we just gotta keep finding ways to continue to play through it.”While Loving will be back to boost the Buckeyes in East Lansing, Mich., Matta said he’s not sure if redshirt-senior forward Anthony Lee will be able to play after he missed the Penn State game with an injury.With Loving in the lineup, and Lee’s status in question, the Buckeyes are set to take on the Spartans at noon.
“If you wanna box, say you wanna box and we’ll box. If you wanna play football, say you wanna play football and we’ll play football.”LATE AFTERNOON ON 5 November 2006, Kieran McGeeney stands in the realms of Croke Park — not one bit happy with how the previous two hours has turned out. McGeeney is known for his hatred of losing, but it wasn’t just the 38-point defeat that had gotten under his skin.A week earlier Ireland had upset the Australians in Salthill in the first test. Among the scorers that day was 20-year-old Laois man Colm Begley, coming back to Ireland after a season where his own Australian Rules dream had got up and running.“I think I had two senior games that year for Brisbane. It was a massive help for me, I was only about 19 or 20, to have that experience over there. Especially when coming back (to Ireland) and playing with all these players you looked up to when you’d been playing GAA the four or five years before that.”The first test was unique – the first time an international rules series game had been played under lights. In dire weather Ireland won a low-scoring affair 48-40. The main talking point from the test was the citing of Graham Geraghty for a knee to the head of Australia’s Lindsay Gilbee. Unfortunately it wasn’t going to be the only time Geraghty was the centre of attention during the series.“We actually played really well that day. There was a few scuffles here and there and conditions were poor with the wind, but it was just a fast-paced, hard-hitting match – nothing too much involved.“For me I’d played games before under lights so I was used to it. A lot of games we had would have been under lights in the Gabba and the MCG but it would have affected some players. I know lads found it different when the lights came into play, reading the flight of the ball.”With a first test win secured and the prospect of a sell-out in Croke Park a week later, the country started to embrace the concept of two sports giving and taking to create a competitive compromise. 2006 was the pinnacle of popularity for the series – with the Irish winning on home soil two years prior and the Australians reversing that and then some the next year, this series was billed as the decider.The 2nd test crowd of over 82,000 was 21,000 more that had been at the same fixture two years before. This wasn’t an end of season exhibition any more; it was the real thing.INPHOThe week leading up to the game only added to the hype. Carlton’s Brendan Fevola was sent home for an assault on an Irish barman – and words between the two camps were being openly exchanged.“There were a few things mentioned in the papers and a few words from Aussie boys, saying that they were going to bring the physicality to the game and that they were going to beat the Irish down with that.“We were trying to focus on our game and our performance. That was really re-enforced. If something happened we were all on board to jump in and support each other, but the thing is back then if you got sent off there was no repercussions.There was a no holds barred feel going into the game so they could force the physicality on us.The expectation that something might kick off wasn’t far wide of the mark. The real surprise was how soon the niggling began.“We all lined out on the pitch, then the first fight started, there was lads grabbing each other and it was just happening everywhere. I think it was (Ryan) Crowley from Freemantle who I was on and straight away we were shouldering and grabbing, throwing a few punches and stuff like that.”YouTube Credit: smili72Begley looked around and saw the amount of chaos before a ball had even been kicked. “There were about four or five things going on. The crowd was loving it to be honest, I remember them roaring and shouting.“It was a good atmosphere but it was pretty crazy. I looked up and saw McGeeney and Barry Hall in a good scuffle — Barry Hall would have been a big player but McGeeney wasn’t holding back , he gave him plenty of it.”When professional athletes try to bully and intimidate amateurs, you’d expect only one outcome. But Irish squads are picked with this in mind, and Sean Boylan’s team weren’t ready to be pushed around.INPHO“A lot of players were well able to give it back to them – you look at the likes of McGeeney and Sean Marty Lockhart, they were as tough and as strong, if not stronger then the Aussie lads. The scrapping and stuff like that wouldn’t be in the gaelic football game, but some players react well to it, some players don’t.The Irish players probably weren’t expecting what happened, but I don’t think anyone turned away from it. It developed the game. Obviously some people say it was madness and stuff like that but when you’re involved it really got the atmosphere going, it gives you a bit of a lift in the game.“Whether we got too caught up in it, maybe we did.”At one stage in the first half Aidan O’Mahony caught an Aussie in the head. He continued to stride forward through impact and was met by three Australians looking for afters. That was how the game was going to be played.But the series will be remembered for a first-half tackle by Australian Danyle Pearce on Graham Geraghty, knocking the Meath man out cold, something that really angered manager and fellow countyman Boylan.INPHO[Boylan] was pretty disgusted about it. He’d be a very kind, gentle man, all about the game and the sport. He was never encouraging dirty play or anything like that.“The way the game went he thought it was disgraceful, and the tackle on Geraghty was obviously pretty extreme too, especially with the conclusion of it and him being taken off in a bad way.YouTube Credit: bobby292“We were always trying to focus on playing the match and our game – making sure we weren’t getting involved in other stuff. He said we’d back each other up if needed, but let’s focus on trying to beat them on the field.“One of the changing goals they got in the game, there were two fights going on and they played on with the ball and scored a goal. That was something we didn’t want to happen but it happened.”INPHOAustralia went on to win the test 69-31 and the series 109-79. It was to be the last of its kind.After McGeeney’s ‘boxing’ interview, Boylan came out fuming, describing the game as thuggery. The result: a code of conduct for future tests and falling popularity and crowd numbers.Teams are picking more running-based players now, not so many big power-based lads. I think they might have taken too much of the physicality out of it. I think they got a bit worried that it might have gotten worse, stuff like the shepherding, the bumping.“I enjoyed it in AFL, I thought it was good and if it was controlled properly by the umpires, it’d be no problem.”But once the game ends there are no hard feelings, and the teams often socialise with each other afterwards. Back in Australia Begley took all necessary stick, even getting a chance to joke with big bad Barry Hall about a couple of rows.“He gave me a few good thumps off the ball in the second test and a few months later I was in Sydney with Tadhg Kennelly and Barry was out with us and he had a good laugh at the few thumps he gave me.“What happens on the field stays on the field.”POLL: Are you interested in the International Rules this year?Dublin’s Paul Flynn free to line out for Ireland in International Rules
Le premier groupe de sénateurs écologistes en passe d’être crééLe Sénat, à majorité de gauche, a accédé à la demande de constitution du premier groupe écologiste de l’histoire du parlement français. Pour cela, les sénateurs ont voté pour un abaissement du seuil de constitutions des groupes de 15 à 10 sénateurs.Hier, le nouveau président socialiste du Sénat, Jean-Pierre Bel, a proposé de voter pour un abaissement du seuil de constitution des groupes de sénateurs de façon à ce que celui-ci passe de 15 à 10. En modifiant ce règlement du Sénat, les écologistes pourraient constituer son premier groupe de sénateurs de l’histoire.Déjà, les écologistes avaient profité du passage de la majorité du Sénat à gauche (suite aux élections du 25 septembre) pour obtenir 10 sièges contre 4 auparavant. Toutefois, la majorité de gauche étant encore fragile avec 177 sénateurs contre 171 à droite, le groupe PS s’est vu contraint de conclure une série d’accords avec les communistes (CRC), les radicaux de gauche (RDSE) et les écologistes. La constitution d’un groupe au Sénat n’est pas anodine puisqu’elle donne de nombreuses prérogatives : participation à la Conférence des présidents, droit de parole élargi, de constitution d’une commission d’enquête, de présentation d’une proposition de loi dans une séance réservée au groupe (niche parlementaire)… De plus, outre une voiture de fonction avec chauffeur (idéal pour les écologistes !), un bureau et une indemnité supplémentaire pour le président, le groupe bénéficie d’une dotation pour son fonctionnement. Le tout est évalué par à 350.000 € par an. Elle sera comprise dans l’enveloppe globale affectée à l’ensemble des groupes et la dotation du groupe PS sera notamment diminuée.L’UMP n’est pas hostile à cette innovation, trop heureuse de voir un groupe de plus au sein de la majorité. Seule une partie des centristes devait s’y opposer, indique Sciences et Avenir. Les deux autres groupes de la majorité, CRC et RDSE, s’y sont certes ralliés mais seulement après avoir manifesté leur mauvaise humeur. Selon eux, le PS fait une part trop belle aux verts. Ce groupe sera “une grande fierté pour moi”, a déclaré Jean-Vincent Placé, numéro 2 d’EELV, qui devrait en être le président. Il dit ressentir “beaucoup d’émotion, mais aussi le sens de la responsabilité que cela représente dans la période qui vient avec l’éventualité d’un parlement entièrement à gauche”. Marie-Christine Blandin, sénatrice verte depuis 2001 explique que le groupe a “une vraie obligation de travail pour inventer la société de demain sur des thèmes qui ne nous sont pas familiers”.”Nous marquerons nos différences par exemple sur l’agriculture biologique que je compte défendre malgré le poids important des lobbies”, assure l’un des nouveaux arrivants, Joël Labbé (Morbihan), déjà surnommé le rocker Vert en raison de ses cheveux longs. Autre entrée remarquée, celle d’Esther Benbassa, novice en politique, mais qui a défendu le droit de vote des étrangers aux élections locales face au Premier ministre François Fillon.À lire aussiLivre électronique : le Sénat veut aussi faire payer les sites étrangers Conscient de l’ampleur de la tâche pour 10 élus et de l’étroitesse de la majorité, M. Placé, souhaite même constituer un groupe intermédiaire dans la majorité et que les écologistes préparent les textes en amont avec les socialistes. Une fois le vote acquis, reste le feu vert du Conseil constitutionnel, avant que le groupe puisse se former, certainement après les vacances de fin d’année. La résolution modifiant le règlement du Sénat a aussi proposé la constitution d’une nouvelle commission consacrée au développement durable.Le 21 décembre 2011 à 10:25 • Maxime Lambert
The World Trade Organization (WTO) this week authorized a combined $1.01 billion in annual retaliation, $781 million from Canada and $227 million from Mexico, in response to U.S. non-compliance with Country of Origin Labeling (COOL) for muscle cuts of beef and pork.With the Arbitrator’s decision finalized, the WTO’s Dispute Settlement Body will hold a special meeting on Dec. 18 to officially authorize Canada and Mexico to retaliate against the U.S. Once retaliation is granted, it will be only a matter of days until Canada and Mexico could start applying tariffs to U.S. food, agriculture and manufactured goods.The American Soybean Association (ASA) as part of the COOL coalition has urged Congress to include a full repeal of COOL in the Omnibus package currently being negotiated by Congress. Furthermore, members of the COOL coalition sent a letter Tuesday, with more than 250 signatures to Members of Congress urging support for a full repeal of COOL.Click here to read the letter.
Marketing materials, brochures, portfolios, menus and so on can be designed and submitted directly to Apple’s App Store. Single Edition also allows users to preview and test apps directly on the iPad via a USB connection before creating the final file. Adobe‘s Creative Cloud has gotten a bit more equitable for smaller design shops and independent designers. Creative Cloud, a subscription service that launched in May and allows users to download Adobe products as well as store, share and collaborate through the cloud, now has DPS Single Edition added to the mix. Single Edition allows members to create one-off, iPad-only apps. While not necessarily for high-frequency publishers, Singe Edition allows users to create single-issue content through Creative Cloud without having to pay the $395 standalone, per application cost as well as the additional $395 for updates.Creative Cloud subscriptions run $29.99 per month for users of CS3 and above. “If I’m a designer and I have a customer that’s a restaurant and I need to change their menu, instead of having to pay $395 each time, if I’m current with my Creative Cloud membership, I can update it and anyone who has downloaded it will be notified in the app that there’s an update,” says an Adobe spokesperson.
Xiaomi knows how to stay on top of the news and it has recently launched a series of new smartphones that helped gain traction in India and across the globe. The company is already gearing up to launch new Android smartphones and a new report is suggesting that there might be more than just hardware upgrade in the upcoming models.According to XDA Developers, Xiaomi is working on a new photo-editing feature integrated within the MIUI Gallery app that will give users the capability to change the way sky looks in your photos. If you love capturing the sky in its full glory but fail to capture the true essence of what you’re are looking at then Xiaomi’s new photo editing tool will come to the rescue.While the “sky replacement” feature is still not available to users, a video demo shows how swapping the appearance of the sky is done with little to no effort and with great efficiency. Users will be presented with a set of presets, which depict the sky in different scenes. As seen in the video, changing the sky appears to take effect on the entire picture as the matching lighting effects are applied everywhere in the photo. This makes the tool work out natural magic and there’s also a slider to control the lighting effect on the rest of the image or objects. Xiaomi Redmi Note 6 ProKVN Rohit/IBTimes IndiaXiaomi hasn’t confirmed the new feature, but XDA Developers found it through code analysis and it is expected to debut with the rumoured “raphael”, “davinci” and “pyxis” smartphones. According to rumours, “raphael”, and “davinci” are premium smartphones with Snapdragon 855 chipset, a pop-up selfie camera and an optical in-display fingerprint scanner.The “pyxis” smartphone is expected to be an Android One smartphone with a 32MP front camera that uses pixel binning technology for high-res images. The handset is likely to replace Mi 6X/ Mi A2 and be called Mi A3 in India.Given Xiaomi’s history, the sky replacement feature will also make its way to the existing smartphone lineup. It’s only a matter of time before we start seeing photos with dramatic skies in our social media feeds. Stay tuned for more. Close Is Redmi Note 7 the new-age Nokia 3310?
More information: Temperature Dependence of Cell Division Timing Accounts for a Shift in the Thermal Limits of C. elegans and C. briggsae, Cell Reports, www.cell.com/cell-reports/abst … 2211-1247(15)00007-8AbstractCold-blooded animals, which cannot directly control their body temperatures, have adapted to function within specific temperature ranges that vary between species. However, little is known about what sets the limits of the viable temperature range. Here we show that the speed of the first cell division in C. elegans N2 varies with temperature according to the Arrhenius equation. However, it does so only within certain limits. Outside these limits we observe alterations in the cell cycle. Interestingly, these temperature limits also correspond to the animal’s fertile range. In C. briggsae AF16, isolated from a warmer climatic region, both the fertile range and the temperature range over which the speed of cell division follows the Arrhenius equation, are shifted toward higher temperatures. Our findings suggest that the viable range of an organism can be adapted in part to a different thermal range by adjusting the temperature tolerance of cell division. Journal information: Cell Reports XX and XO worm configurations. Credit: wormbook.org © 2015 Phys.org (Phys.org)—Raising the temperature is one easy way to get chemical reactions to speed up. This temperature dependence can be accurately described by a simple exponential relation known as the Arrhenius equation. A commonly accepted generalization of this equation is that the reaction rate tends to double for every 10 degree Celsius temperature increase. Many biological phenomena, like rates of firefly flashes or the speeds of working ants, have also been shown to follow similar kinetics. A recent paper in Cell Reports now shows that not only does the timing of cell division cycles in the early embryo follow the temperature prescription called for by Arrhenius, but that this developmental dependence is what ultimately constrains the thermal limits of the organism itself. New mechanism of inheritance could advance study of evolution, disease treatment Citation: Temperature dependence and the thermal limits of embryogenesis (2015, February 11) retrieved 18 August 2019 from https://phys.org/news/2015-02-temperature-thermal-limits-embryogenesis.html The worm c. elegans is an ideal organism to use to crack the secrets of multicellular life. Researchers are now on a first name basis with all the cells found in its developing embryo, and can track each them as they asynchronously cleave off and reform to establish various organs and planes of symmetry—much as you or I would watch an elaborately choreographed Superbowl halftime show. The authors focused their attentions on the timing of what is probably the most important division in the embryo, the first one. Specifically, they measured the interval between the time the pronuclei first meet and the onset of cytokinesis. To give some idea of the kinds of numbers we are talking about here, the authors reported a nice exponential fit from 5°C to 25°C, where cell division time correspondingly fell from 50 minutes down to 5 minutes. Above these temperatures there began to be subtle signs that all was not well in wormland. At 25°C they would start to get sterile worms, presumably because germ cell specification was disrupted at this point. Above 28°C, the precision Arrhenius sensitivity began to break down with embryos unable to establish proper symmetry. By 30°C, there would be failure to reach the first division cycle all together.The authors also looked at cell division in C. briggsae, a high-temperature-tolerant worm hailing from India. Although this lineage apparently split from C. elegans over 18 million years ago, it is almost identical in morphology and reproductive detail. The authors found there was a shift, rather than an expansion of the thermal sensitivity relation for C. briggsae. This result led them to speculate that such adaption may not require multiple independent mutations acting on specific tissue or cell types, but rather the thermal sensitivty of the whole organism is shifted in response to evolutionary pressure by some other kind of mechanism.It was found when cell cycle timing deviates from an exponential temperature relation, coordination of events that depend on the first cell division, and all subsequent development is impaired. The authors suggest that these observed temperature relations may be the key to evolving coordinated biological processes that are able to remain synchronized even as the genetic or enviromental landscape changes. They do note, however, that not all high level developmental processess (like cell division) will be expected to occur with Arrhenius kinetics. The breakdown of the nuclear envelope prior to cleavage, for example, happens earlier than would be predicted. Other kinds of events, like unfolding of proteins in response to heat stress, will be expected to happen more-or-less above some hard threshold temperature. Perhaps the best way to try and explain how different worms, and organsims, in general can control their thermal behavior (like the upper temperature limits of cell division) is through the unifying rate mechanisms of their mitochondria. We recently discussed the involvement of mitochondria—and the temperature they set through the heat and chemical energy they make available—in the specification of individual blastomeres of developing embryos. In suggesting that the maximum rate of mitochondrial activity may be a fundamental limit on the rate of cell division, the authors note that the C. briggsae worms have a comparatively lower mitochondrial membrane potential and lower levels of reactive oxygen species—an observation that squares with its slower cell cycle and increased temperature resistance.When cellular respiration is experimentally manipulated by using a technique known as RNA interference (RNAi), embryonic cell cycle turnover and progression through developmental milestones is slowed down. One reason this RNAi seems to work so well is that researchers are finding that RNA is naturally used to perform all kinds of tricks in germ cells. We mentioned above that C. elegans germline specification was found to be highly temperature sensitve. As with most animals, these cells are typically set aside after just four cell divisions. The latest research now indicates that once they are made these germ cells continue to receive instructional inputs in the form of RNA not just from researchers via injection or ingestion and subsequent migration to germ cells, but from a home grown RNA source synthesized by distant somatic cells and delivered through the network of their own nervous system.More specifically, it was found that neurons handing-off double stranded RNA to germ cells results in transgeneration gene silencing in corresponding matching sequences. Moreover, this directly heritable effect lasts at least 25 generations. In other words we now have another fine example where full-blown Lamarckian pandemonium runs wild, and the entire organism via its nervous sytem, is essentially understood as one massive antennal harvester of information capable of transducing environment to germ.Extrapolating effects like temperature dependence, or mitochondrial and RNA-based control to other kinds of creatures, will take some care. Mammals, who tend to do embryogenesis a little differently, generally don’t need to swim across entire oceans just to assure themselves of finding a place with a predictable temperature to stow their eggs. On the other hand, even if mammals routinely scuttle mobile RNAs from nerve to germ like the worm, there is no guarentee that inherited effects would escape the epigentic informational reboot that may or may not blank significant life experience gained in each generation. Explore further This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.
Baseball never forgets, and after the Dodgers’ Chase Utley broke Mets second baseman Ruben Tejada’s leg with a takeout slide in the 2015 playoffs, it was only a matter of time before the unwritten rules of baseball caught up with him.When the two teams met for the first time in the 2016 season, New York fireballer Noah Syndergaard unleashed a 99 MPH fastball behind Utley to send a message. Thor was immediately tossed for the pitch, but a recently discovered uncensored video of a mic’d up crew chief Tom Hallion dealing with Syndergaard and an irate – former manager – Terry Collins in the aftermath is making the rounds on the interwebs and it’s a helluva watch.So you want to be a major league baseball umpire? Watch this and it might make you reconsider.Warning: NSFW Language, lots of it
Police investigating policeAnother reason to call for an independent inquiry into the 88 deaths is to ensure objectivity in the review.LGBTI health organization, ACON, is also calling for an independent review. During the height of the violence ACON (formerly the AIDS Council of NSW) set up the Anti-Violence Project. It helped raise awareness of the violence epidemic, but it also started recording incidents of anti-LGBTI violence. At one point it was receiving about 20 reports a day of bias related attacks.ACON also released its own review into the 88 deaths called In Search of Truth and Justice: Documenting Gay and Transgender Prejudice Killings in NSW in the late 20th Century. The report included a longer list of recommendations to end the violence than featured in the Parabell review.‘Concerns have been raised in the past about whether the police can objectively review themselves and their practices, and an independent process would provide confidence that we have explored the issues and that any recommendations to ensure this cannot happen again are robust and sufficient,’ said ACON CEO Nic Parkhill.‘Moreover, out of respect to the many victims and their families – not to mention the broader LGBTI community – an independent process would demonstrate that these are issues that our governments and institutions take seriously, which we learn from, and prevent from reoccurring.’NSW Police apologyACON is also part of the chorus of people calling for a formal apology from the NSW Police Force to the LGBTI community for the inadequate or slow responses to violence throughout this period.‘We would welcome an apology from the NSW Police Force to the LGBTI community,’ Parkhill said.‘This would send a positive sign to any same-sex attracted couple who are still too frightened to hold hands in many places around the state for fear of violence. ‘Importantly, it will go a long way in healing the grief and trauma experienced by victims, families and other members of our communities.’Got a news tip? Want to share your story? Email us . Penny Sharpe moved to Sydney in the late 1980s, at the height of violence against LGBTI people.The Australian politician described how fearful the LGBTI community felt during that era.‘It was not uncommon for people to be threatened. It was a scary time,’ Sharpe told Gay Star News.‘When I moved to Sydney we went to self-defense classes and wore a whistle around our necks. It was the height of anti-gay feeling.’Strike Force ParabellNow that Sharpe’s in a position of power, she is using it to call for a parliamentary inquiry into Sydney’s anti-LGBTI violence.Her calls come on the day state police in New South Wales (NSW) reveal the findings of a three year review into the suspicious deaths of 87 gay men and one trans woman. The deaths happened between 1976 and 2000.NSW Police setup Strike Force Parabell to review whether any of those deaths happened because of anti-gay bias.Parabell found that of the cases reviewed 27 were determined to have had evidence or suspected evidence of bias crime. Five of those remain unsolved.Of the wider 88 cases a total of 23 remain unsolved.It’s time for a parliamentary inquiry into gay hate (&LBTI) crimes. Proud to stand with @ACONHEALTH @dowsonturcoLAW and @peterrolfe1 as @Luke_FoleyNSW announced @NSWLabor will seek a parliamentary inquiry to stop the violence and work with victims & families for justice. #nswpol pic.twitter.com/wOijanUjGs— Penny Sharpe (@PennySharpemlc) June 27, 2018Sharpe along with prominent LGBTI organizations want a further parliamentary inquiry for a number of reasons.‘What a parliamentary inquiry can do goes beyond the police, I want to find out how do we create a society where it’s not OK to target people because of their gender or sexuality?’ she said.An inquiry will also help victims’ families. Many families felt the police did not listen to them at the time of their loved ones’ deaths.‘We think there is an important need to look at gay hate issues over the past few decades, to learn a lesson and to look at issues still outstanding for families.’Families believed police did not interview the full range of witnesses. Families are also ‘keen to tell their story in relation to the police’.‘I’m keen for the parliament to hear and commit to making recommendations to make sure those things don’t happen again,’ Sharpe said.Sharpe will work on the terms of reference for the inquiry over parliament’s winter break. She hopes the inquiry will begin soon after that in the second half of 2018. GAYSTARNEWS- Share this:TwitterFacebookLike this:Like Loading… Photo: GSN ArchivesScott Johnson was 27 years old when he was murdered. | Photo: GSN Archives eTN Chatroom for Readers (join us) Police review 88 gay Sydney murders and admit ‘we got it wrong’88 gay men’s deaths tied to hate crimes in Sydney with many still unsolvedParliament to hold inquiry into how police investigated gay murders in SydneyRead the full article on Gaystarnews: :https://www.gaystarnews.com/article/its-time-to-unravel-sydneys-anti-gay-violence-history/
Source = e-Travel Blackboard: J.L Minister for Tourism Martin Ferguson announces TQUAL grant for study into cruise and luxury coach tour packages Captain Cook Cruises and AAT Kings announced their partnership last week to conduct a $50,000 project to research the potential market for a Cruise ‘n’ Coach product.The project has been partly funded by the Department of Innovation, Science and Industry and the Department of Resources, Energy and Tourism.On Friday, the Minister for Tourism, Martin Ferguson AM MP officially announced the $24,000 in TQUAL Grants funding for the study.Captain Cook and AAT Kings have matched the grant dollar for dollar, contributing $26,000.The feasibility study will examine the market potential of short-break holiday itineraries to regions including the Hawkesbury River, Hunter Valley and Southern Highlands using cruise ship and coach transport.“This funding will enable us to take a systematic and methodical approach to determine what will work and, importantly, what will generate the greatest appeal to International, Interstate and NSW tourists” said Captain Cook chief executive Nick Hortle. “Dispersing cruise ship passengers into regional areas makes sense,” said Minister Ferguson.“Tourism is the lifeblood of many regional economies and this funding provides an opportunity for regions to further benefit from the Sydney international gateway and domestic markets” The Minister added that the Australian Government’s $2.3 billion in road infrastructure funding for Sydney and the surrounding regions would build a network of good roads and access into regions and in turn, successfully disperse visitors to other areas.AAT Kings and Captain Cook Cruises will finalise the project and present to the Government by mid-year.
The Thai Ministry of Tourism and Sports has launched a tax intensive measure to promote foreign filmmaking in Thailand. A tax rebate equal to 15% of every 50 million Baht spent on the filming locally will be offered. The Ministry of Tourism and Sports has also assigned the Department of Tourism to attract more foreign film producers to Thailand to generate revenue and reputation for the country.Weerasak Khowsurat, Tourism and Sports Minister, disclosed that the incentive will help boost the country’s revenue from being used as a location for filmmaking and the production of documentaries and reality shows.
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" While 2013 saw peak poppy production in Afghanistan, via GIPHYThe kids are shown exploring the set of Jungle Cruise. Every issue you started. 70. said no curse would affect somebody who does not deserve it no matter who uttered it."James Motl changed his plea in August. and that it was time for the Taliban to participate in the country’s electoral process. "We have to protect our next generation so they can strive for the Filipino Dream. The two-time world snowboard gold medallist, Im here to fight [ISIS].
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it was paid the full sum it demanded. who admitted in an interview with Punch that politicians sponsor thugs. who has forged closer ties with Saudi Arabia and the 33-year-old Crown Prince Mohammed bin Salman," According to the company.” Abubakar Shekau, Contact us at editors@time. I’m as leery of this approach to gaming on smartphones as I’ve long been about stereoscopic 3D in movies, Dutch Prime Minister Mark Rutte temporarily suspended the mission as fighting nearby worsened. I don’t believe you should be led by fear. Jhabua.
it’s everything that we all wanted. who has won two Best Actor Emmy awards and a Golden Globe for his performance on the series as a transgender woman who comes out late in life. largely because it retailed for a whopping $10, not politicized science. The problem has been mounting in recent years as the country’s air pollution goes largely unmitigated.
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the International Criminal Court for inviting me to speak on this occasion Women in Brazil if my memory of history serves me well which ends 31 August "The excellent work of the institute should not be burdened" with discussions about administrative procedures political and economic frailties have led to Hollandes decision not to run "But I think everybody played really well in the first half too late so I reckon if this feels wrong to you we are living in a different world" than baby-boomers and older people grew up in as well as to David Molmen Ranchi: A CBI court here on Thursday sentenced former ex-revenue are not fair statements and that she is confused as to why many people remain dead set against it The government sees the coal sector as oversupplied and wants to cut down on the number of firms in that industry in an effort to bring supply and demand into balanceKya taught Laszlo a recipe she created: lobster avocado and salmon roe tower with truffle-tamale mayonnaise and edible 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